Topical Products – When CBD is applied topically directly to the skin, it doesn’t reach the bloodstream but can be absorbed through the skin’s surface to interact with nearby cannabinoid receptors.
Human skin in general has low permeability, which means it blocks most substances from entering. The skin has a particularly low absorption rate for cannabinoids, so application of CBD balms, salves, and lotions need to be heavy enough to overcome this barrier. However, when applied liberally, CBD is permeable to the skin through its pores.
Finally, you have receptors called TrpV1 in your body that keep track of your body temperature. When triggered they generate heat, which can soothe pain receptors. Using this method, CBD can cause these receptors to be hyperactive for a period of time, causing the pain receptors to get hot, and desensitise them. Meaning if they’re desensitised, they can’t detect pain.